The Future of Water.

In collaboration with prestigious universities across the US and Europe, we have uncovered novel structural and chemical properties demonstrating the antioxidant effects of Weo Water, its unique structure, and the 200+ bio-species, created as a result of its restructuring at the molecular level.

What is Weo Technology?

 

Weo uses a patented, diamond electrolysis technology to produce a unique water made up of blended properties and components. This proprietary mixture includes dissolved oxygen (O2), molecular hydrogen (H2), antioxidant properties, reactive oxygen species (ROS) and combinations of each.

In addition to the production of both oxygen and hydrogen species, we have discovered the water structural and physical changes associated with the promotion of health benefits. 

1.

What Differentiates Weo Technology and Weo Water From Competitors?

Weo Technology is a unique wellness device whereby we use a patented diamond electrolysis technology to produce a unique water made up of blended properties and constituents.  

Our unique technology, using man made diamond and electricity to create specific changes in the water molecule is the guarantee of a safe and efficient  drinking water. 

Weo technology keeps all biomolecules present in water thus we get the benefits of both hydrogen and oxygen.

Separately, we are not adding anything to the water and there is no change in pH making it suitable for daily consumption.

2.

What are The Unique Constituents of Weo Water?

Weo electrolysis technology generates water with unique properties and creates different species with demonstrated health benefits. While Weo water is made up of both oxidants and antioxidants, than its antioxidant properties appear to be more pronounced than it oxidant properties, as demonstrated by internal studies showing a reduction of its Oxidation Reduction Potential (ORP) after electrolysis, and scanning probe microscopy studies including kelvin force microscopy done in collaboration with University of Michigan showing negative charges as low as -550mv. Moreover, investigation of the geometries of these bioactives and the values of their antioxidant parameters such as their power energy spectrum indicate greater electron donating capabilities Further, our internal lab studies using galvanic and amperometric micro sensors have demonstrated increased concentration of both dissolved oxygen and molecular hydrogen, which has been deemed a selective antioxidant.  These increases have also been confirmed with scanning probe microscopy techniques done in collaboration with multiple academic partners.

Taken together, both experimental and theoretical evidence indicates that Weo water has unique properties and includes a mix of both oxidizing and reducing species.  

3.

Weo Technology Promotes Healthy Aging

Aging is characterized by a progressive loss of physiological integrity, leading to impaired biological function and an increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies including  cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. The process of aging is multifactorial and involves increased amounts or an impaired ability to address and mitigate oxidative stress (inflammation). This imbalance in “REDOX” (reduction-oxidation ratio) leads to unbalanced oxidant-burden, which leads to chronic inflammation in the body. Persistent oxidative stress also leads to cellular senescence, another important hallmark of aging, and is involved in several age-related conditions and illnesses. 

Weo water has powerful antioxidant properties with constituents that selectively scavenge damaging reactive oxygen species (ROS). Recent internal studies have also demonstrated Weo water can modulate the phenotype of senescent cells after oxidative stress injury.   It was determined that Weo water modulated markers of cellular senescence, modulated the expression of SASP factors and stress response genes.  This reduction in the expression of SASP factors and stress-related genes suggests that Weo water acts as a protective factor, thereby reducing oxidative stress in normal cells collectively suggesting that Weo water is positioned to have a positive impact on longevity and age-related diseases.

Using this novel technology to produce a unique water made up of blended properties and components, including mixtures and combinations of dissolved molecular oxygen (O2), molecular hydrogen (H2), antioxidants, and ROS provides new avenues for senescence- related interventions. In addition to the production of both oxygen and hydrogen species, the water undergoes structural and physical changes that could be associated with other aging related health benefits. 

  • Durackova Z. Some current insights into oxidative stress. Physiol Res. 2009
    Fu Z, Zhang J, Zhang Y. Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases. Oxid Med Cell Longev. 2022 Mar 18;2022:2249749. doi: 10.1155/2022/2249749. PMID: 35340218; PMCID: PMC8956398.
    Hong Y, Chen S, Zhang JM. Hydrogen as a selective antioxidant: a review of clinical and experimental studies. J Int Med Res. 2010;38⑥:1893-903.
    López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 2013 Jun 6;153(6):1194-217. doi: 10.1016/j.cell.2013.05.039.
  • López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. Hallmarks of aging: An expanding universe. Cell. 2023 Jan 19;186(2):243-278. doi: 10.1016/j.cell.2022.11.001. Epub 2023 Jan 3.
  • Ohsawa, I., Ishikawa, M., Takahashi, K. et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med 13, 688–694 (2007).
  • Rahman, M.H.; Jeong, E.-S.; You, H.S.; Kim, C.-S.; Lee, K.-J. Redox-Mechanisms of Molecular Hydrogen Promote Healthful Longevity. Antioxidants 2023, 12, 988. https://doi.org/10.3390/antiox12050988
  • University of Miami (NAGBL) Effect of Weo Water Samples on Cellular Senescence. Weo Internal Nov 2018
  • University of Miami (NAGBL)Weo Water Effect on Caenorhabditis elegans lifespan.. Weo Internal May 2019
  • Zanini D, Todorovic N, Korovljev D, Stajer V, Ostojic J, Purac J, Kojic D, Vukasinovic E, Djordjievski S, Sopic M, Guzonjic A, Ninic A, Erceg S, Ostojic SM. The effects of 6-month hydrogen-rich water intake on molecular and phenotypic biomarkers of aging in older adults aged 70 years and over: A randomized controlled pilot trial. Exp Gerontol. 2021 Nov;155:111574. doi: 10.1016/j.exger.2021.111574. Epub 2021 Oct 1. PMID: 34601077.
  • Settineri, R et al. Effects of Hydrogenized Water on Intracellular Biomarkers for Antioxidants, Glucose Uptake, Insulin Signaling and SIRT 1 and Telomerase Activity. 2016/10/14. N1 – doi: 10.12691/ajfn-4-6-4

4.

Weo Technology Enhances Skin Health

Oxidative stress emerges when an imbalance exists between free radical formation and the capability of our body to clear them. For instance, an excess of hydroxyl radical and peroxynitrite can cause lipid peroxidation, thus damaging cell membranes and lipoproteins.  The resulting impact on our skin directly damages its protein (collagen), lipid and DNA causing external signs of aging such as wrinkles.  Weo water has been shown to have antioxidant properties that selectively rids the body of damaging free radicals. Bioatives in Weo water have also been shown to upregulate endogenous antioxidants such as glutathione via Nrf2 pathway activation. Clinical trial data on Weo bioactives, in vivo Weo lab studies using skin models, as well as results based on our most recent human beta test are part of a robust repertoire of positive findings on skin health. 

In partnership with a European research institute, studies were performed to determine if Weo water could accelerate wound healing in cultured connective tissue fibroblasts, the most common cell type represented in connective tissue and are the main cell type present in skin connective tissue (dermis). These cells produce a diverse group of products including collagen. The studies concluded, the addition of Weo water to cell culture resulted in stimulation of migration and proliferation of connective tissue cells which caused an accelerated wound healing process compared to controls, demonstrating Weo’s positive effect on skin health. 

In collaboration with another research laboratory in Canada, the effects of Weo water on atopic dermatitis (eczema) in an in vivo model were investigated. It was found that Weo water demonstrated an ability to positively modulate atopic dermatitis by reducing skin degradations in quantity but also in size. These effects were observed after approximately 15 days. According to these findings, we are also now exploring how Weo may be helpful for atopic dermatitis patients in a clinical setting. 

Results of our first survey in people consuming Weo water we found that nearly half of participants saw improvements in their skin in approximately 2 weeks, including attenuation and improvement of symptoms of eczema. 

  • Dartsch Scientific. Effect of Weo water technology on cell regeneration/wound healing process of cultured connective tissue fibroblasts. Weo Internal Nov 2017
  • Dartsch Scientific. Weo water dose-dependent stimulation of migration and proliferation of connective tissue cells. Internal Nov 2017
  • Dartsch Scientific. Effect of different BDD electrodes on the cell regeneration/wound healing process of cultured connective tissue fibroblasts. Weo Internal Dec 2017
  • Dartsch Scientific. Effect of BDD-Condias electrode in comparison to BDD-Si electrode on the cell regeneration/wound healing process of fibroblast cells. Weo Internal April 2018
  • Dartsch Scientific. Effect of a DiaCCon Sil* electrode on the cell regeneration/wound healing process of cultured connective tissue fibroblasts. Weo Internal June 2018
  • Charles River. Evaluation of Oxazolone-induced Atopic Dermatitis Model in Mice. Weo Internal. Dec 2018
  • Dartsch Scientific. Effect of BDD Si electrode on cell regeneration/wound healing of cultured pig intestinal epithelial cells. Weo Internal May 2018
  • University of Miami (NAGBL) Effect of Weo Water Samples on Cellular Senescence. Weo Internal Nov 2018
  • Cortez, B., S. Arroyo, Desprez, PY et al Investigation of the effects of Weo water on cellular senescence in both normal human fibroblasts and cancer cells. California Pacific Medical Center/Buck Institute/Weo lab . Weo Internal. Aug 2023
  • Tanaka Y, Miwa N. Repetitive Bathing and Skin Poultice with Hydrogen-Rich Water Improve Wrinkles and Blotches Together with Modulation of Skin Oiliness and Moisture. Hydrogen. 2022; 3(2):161-178
  • Kato S, Saitoh Y, Iwai K, Miwa N. Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes. J Photochem Photobiol B. 2012 Jan 5;106:24-33.
  • Tanaka Y, Xiao L, Miwa N. Hydrogen-rich bath with nano-sized bubbles improves antioxidant capacity based on oxygen radical absorbing and inflammation levels in human serum. Med Gas Res. 2022 Jul-Sep;12(3):91-99. 
  • Sergej M. Ostojic et al. Hydrogen-rich water as a modulator of gut microbiota? Journal of Functional Foods, Volume 78,2021,
  • 104360, ISSN 1756-4646, https://doi.org/10.1016/j.jff.2021.104360.
  • Kiyoi T, Liu S, Takemasa E, Hato N, Mogi M. Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress. Geriatr Gerontol Int. 2023 Apr;23(4):304-312. doi: 10.1111/ggi.14562. Epub 2023 Feb 20.
  • Tanaka Y, Saitoh Y, Miwa N. Electrolytically generated hydrogen warm water cleanses the keratin-plug-clogged hair-pores and promotes the capillary blood-streams, more markedly than normal warm water does. Med Gas Res. 2018 Apr 18;8(1):12-18.
  • https://nationaleczema.org/research/eczema-facts/
  • Weo lab. The effects of Weo water on human consumption. Weo Internal. Aug 2019. 

5.

Weo Technology Improves Exercise Performance

Intermittent exercise capacity reflects the ability to complete repeated bouts of exercise followed by inadequate periods of rest. In field-based team sports (soccer, rugby, football, etc) performance is based on not only the ability to generate maximal power output, but also the ability to recover from maximal or near maximal efforts and then further to be able to do it repeatedly over time, employing both aerobic and anaerobic metabolic systems.  While there are many factors that can contribute to each of these components within intermittent exercise performance, the primary factors responsible for the ability to generate and maintain high muscle power output over successive sprints include adenosine triphosphate (ATP) depletion and resynthesis rate, and neuromuscular excitability associated with disturbances in intra- and extracellular ion homeostasis.

Recovery between efforts is generally believed to be dependent on high aerobic fitness and capacity.  The efficiency of these processes rely on many factors; two of which are maintaining the proper balance of oxidation and reduction (REDOX) and the ability of O2 transport and delivery to tissues via hemoglobin levels in red blood cells. 

Weo water characterization studies have shown Weo water contains increased concentrations of dissolved oxygen and molecular hydrogen, as well as reduced ORP values indicating increased antioxidant properties.  These properties and bioactives have ergogenic effects on both aerobic and anaerobic power and recovery, both of which are essential for intermittent exercise performance.  

Reactive Oxygen Species (ROS) are produced within contracting skeletal muscle and at low levels, and may act as important signaling molecules; however, their accumulation at higher levels can negatively affect a number of processes involved in the generation of muscle force and power and induce fatigue.  A bioactive in Weo water has been shown to have an antifatigue effect across different modes of exercise, including endurance, strength-endurance drills, cycling anaerobic power output, maximal isokinetic muscle strength, and during prolonged, intermittent sprints.

Further, antioxidants have been shown to have beneficial effects on performance short term recovery when adaptation is not the primary aim.  For example, heart rate recovery was improved in Bulgarian football players drinking electrochemically activated water with reduced ORP (similar to Weo water) after exercise tolerance testing.

Dissolved oxygen literature shows positive results on some aspects of exercise performance and recovery .  Specifically, the presence of a normal amount of Hemoglobin (Hgb) per volume of blood increases the amount of O2 that can be transported about 70-fold. Preclinical studies, both in cells cultured with Weo water-based media and animals administered Weo drinking water, have shown increased red blood cell (equine) and hemoglobin concentrations (equine and mice) and decreased expression of pro-inflammatory markers (cells).  Moreover, pre-clinical studies have shown that Weo water has a profound effect on ATP synthesis indicating that Weo bioactives are working at the level of the mitochondria. An increased amount of Hgb also increases the amount of O2 that can be delivered to the tissues and O2 transport capacity correlates directly with aerobic performance. This is also evidenced by studies showing an increase in performance after infusion of red blood cells and by the strong correlation between total Hgb and maximal O2 uptake (VO2,max) in athletes. 

Collectively, when we consider the research and experimentations all around the world on the components and properties of electrolyzed, reduced water as well as the pre-clinical data, we were able to conclude that Weo water is a promising strategy to mitigate the decline that comes with repeated bouts of intermittent exercise via enhanced recovery between bouts and mitigation of muscle fatigue and its potential effects on both aerobic and anaerobic metabolism.

  • Allen, D.G., G.D. Lamb, and H. Westerblad (2008). Skeletal muscle fatigue: cellular mechanisms. Physiol. Rev. 88: 287-332.
  • Ara, J.; Fadriquela, A.; Ahmed, F.; Bajgai, J.; Sajo, M.E.J.; Lee, S.P.; Kim, T.S.; Jung, J.Y.; Kim, C.S.; Kim, S.-K.; et al. Hydrogen water drinking exerts anti fatigue effects in chronic forced swimming mice via antioxidative and anti-inflammatory activities. Biomed. Res. Int. 2018, 2018, 2571269. 
  • Berglund B., Hemmingson P. (1987). Effect of reinfusion of autologous blood on exercise performance in cross-country skiers. Int. J. Sports Med. 8, 231–233 10.1055/s-2008-1025661
  • Botek M, Khanna D, Krejčí J, Valenta M, McKune A, Sládečková B, Klimešová I. Molecular Hydrogen Mitigates Performance Decrement during Repeated Sprints in Professional Soccer Players. Nutrients. 2022 Jan 25;14(3):508. doi: 10.3390/nu14030508. PMID: 35276867; PMCID: PMC8838970.
  • Botek, M.; Krejčí, J.; McKune, A.J.; Sládečková, B. Hydrogen-rich water supplementation and up-hill running performance: Effect of athlete performance level. Int. J. Sports Physiol. Perform. 2020, 15, 1193–1196.
  • Da Ponte, A.; Giovanelli, N.; Nigris, D.; Lazzer, S. Effects of hydrogen rich water on prolonged intermittent exercise. J. Sports Med. Phys. Fit. 2018, 58, 612–621. 
  • Enoka RM, Duchateau J. Muscle fatigue: what, why and how it influences muscle function. J Physiol. 2008 Jan 1;586(1):11-23. doi: 10.1113/jphysiol.2007.139477. Epub 2007 Aug 16. PMID: 17702815; PMCID: PMC2375565.
  • Ferreira, L.F., and M.B. Reid (2008). Muscle-derived ROS and thiol regulation in muscle fatigue. J. Appl. Physiol. 104: 853-860.
  • Fleming, N, Vaughan, J, Feeback, M. Ingestion of oxygenated water enhances lactate clearance kinetics in trained runners. J Int Soc Sports Nutr 2017;14:1–7. 
  • He,Feng et al Redox Mechanism of Reactive Oxygen Species in Exercise 2016 Frontiers in Physiology 2016 10.3389/fphys.2016.00486
  • Hong Y, Chen S, Zhang JM. Hydrogen as a selective antioxidant: a review of clinical and experimental studies. J Int Med Res. 2010;38⑥:1893-903.
  • Javorac, D.; Stajer, V.; Ratgeber, L.; Betlehem, J.; Ostojic, S. Short-term H2 inhalation improves running performance and torso strength in healthy adults. Biol. Sport 2019, 36, 333–339. 
  • Timón R, Olcina G, González-Custodio A, Camacho-Cardenosa M, Camacho-Cardenosa A, Martínez Guardado I. Effects of 7-day intake of hydrogen-rich water on physical performance of trained and untrained subjects. Biol Sport. 2021 Jun;38(2):269-275. 
  • Yang M, Dong Y, He Q, Zhu P, Zhuang Q, Shen J, Zhang X, Zhao M. Hydrogen: A Novel Option in Human Disease Treatment. Oxid Med Cell Longev. 2020 Sep 5;2020:8384742. doi: 10.1155/2020/8384742. PMID: 32963703; PMCID: PMC7495244.

6.

Weo Technology Boosts Immune Function

Weo has performed many positive studies demonstrating its positive effects on immunity.  In partnership with the #1 human health research institution in France, esteemed researchers investigated the effect Weo water has on different aspects of the immune system. The results demonstrated Weo water induces many positive effects using both in vitro and in vivo models as follows:

Weo’s effect on NK and T cells

This study evaluated the impact of Weo water on peripheral blood mononuclear cells (PBMC) and also observed effects on the human immune system cells – NK (Natural Killer) and Thymus lymphocytes (LT). It was concluded that Weo water lowers the cytotoxic activity of NK cells activating an immunoregulatory phenotype of NK cells and decreases the production of pro-inflammatory cytokines. Furthermore, Weo water exerted differential effects on T cells subsets, mainly affecting the percentages of CD4 T compartment (different subsets of CD4 T cells) without any relevant effect on CD8 T cell compartment. This suggests that Weo water may have potential to induce regulatory T cell proliferation. 

Weo Water & Dynamism of Immune System

This study investigated whether Weo Water could contribute to preserving the balance between innate and adaptive immunity using an ex vivo model (PBMCs).  Results of this study concluded Weo, in contrast to tap water, helps maintain the healthful balance of adaptive to innate immune cell ratio in peripheral blood. This study also found that Weo maintained the viability of adaptive and innate immune cells and also had a more pronounced effect on major subtypes of adaptive T and NK cells of middle-age donors, suggesting that Weo Water might have a more pronounced effect on the immune system of middle-age/elderly individuals than on young ones.  Lastly, Weo Water increased the percentage of CD14 CD56 monocytes, a measure of a fine-tuning of  circulating monocytes activation towards safeguarding against tumor development.  Together, the data from this study suggest that Weo Water could attenuate age-related changes in immune function (inflammaging) in particular in terms of protection against pathogens and decline in efficiency of vaccinations. 

Weo & Frequency of early hematopoietic progenitors’ populations in young and old mice

The findings from this study indicate Weo water has a positive impact on old mice, in particular the CLP population, which is the main population responsible for producing the B-lineage (cells that produce antibodies upon vaccination). This signifies that a less robust response to immunization, often observed in elderly,  could be moderated by drinking Weo water, which would help maintain this pool of cells.  This also suggests drinking Weo at younger age may maintain the pool of HSC and progenitors that are responsible for maintaining a healthier immune system with aging.

Weo Water and Immune System: Functional Study

This study investigated the effect on innate immunity (monocytes and natural killer lymphocytes) and adaptive immunity (T lymphocytes) of peripheral blood in an ex vivo culture. It was found that application of Weo water, unlike tap water, resulted in a maintenance of homeostasis of the immune system. Weo water application was also found to maintain the pool of naive and memory T cells, demonstrating a specific immune response which is a mechanism by which pathogens and cancer cells are eliminated.  Maintenance of the pool of naive T cells also prevents senescence – the process by which cells no longer divide yet remain metabolically active, secreting what are known as SAPS factors.  These factors induce inflammation and are associated with multiple chronic diseases.  This study also demonstrated that Weo water maintains the pool of natural killer monocytes and lymphocytes and thus may contribute to another effective innate immune response against pathogens and cancer cells.  Weo water ensures that monocytes are kept in a quiescent state and therefore may be an effective protection against systemic exacerbated inflammation (cytokine storm).

In summary, Weo water has demonstrated positive effects on the immune system in multiple areas and by many different mechanisms of action. 

  • Charles River. The effects of Weo water on senescence of the immune system. Weo Internal. Oct 2021
  • CNRS. Weo water’s effects on cytokine serum levels. Weo Internal. Aug 2019
  • Durackova Z. Some current insights into oxidative stress. Physiol Res. 2009
  • Hong Y, Chen S, Zhang JM. Hydrogen as a selective antioxidant: a review of clinical and experimental studies. J Int Med Res. 2010;38⑥:1893-903.
  • INSERM. Weo water’s effect on NK and T cells. Weo Internal. Dec 2020. 
  • INSERM. Weo Water & Dynamism of Immune System. Weo Internal. June 2021. 
  • ISERM. Weo water and Immune System: Functional Study, Dec 2021.
  • López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 2013 Jun 6;153(6):1194-217. doi: 10.1016/j.cell.2013.05.039. 
  • López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. Hallmarks of aging: An expanding universe. Cell. 2023 Jan 19;186(2):243-278. doi: 10.1016/j.cell.2022.11.001. Epub 2023 Jan 3.
  • Ohsawa, I., Ishikawa, M., Takahashi, K. et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med 13, 688–694 (2007). 
  • Tian Y, Zhang Y, Wang Y, Chen Y, Fan W, Zhou J, Qiao J, Wei Y. Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis. Front Physiol. 2021 Dec 20;12:789507. doi: 10.3389/fphys.2021.789507. PMID: 34987419; PMCID: PMC8721893.

7.

Weo Technology Has Positive Effects on Metabolic Health

The state of one’s metabolic health determines whether or not the body is physiologically optimized.  Unfortunately, 1 in 3 adults in the United States have a Metabolic Syndrome (National Institutes of Health 2002).  This ubiquitous syndrome is characterized by a constellation of metabolic and anthropometric abnormalities, which include excess weight, insulin resistance, hyperglycemia, hypertension, low concentration of HDL-cholesterol (HDL-C), and dyslipidemia.  MS is associated with several medical risk factors that increase risk of developing cardiovascular disease, stroke, and type 2 diabetes and obesity, which has become a worldwide pandemic. The sequelae of this condition increase the risk of cardiovascular and neurological disease and increased mortality. Its pathophysiology is believed to be associated with redox dysregulation, excessive inflammation, and perturbation of cellular homeostasis. 

Weo water electrolysis technology has been demonstrated to produce powerful bioactives that promote oxidative/antioxidative balance in the body, thereby aiding overall metabolic health. More specifically, these bioactive elements have been shown in clinical studies to attenuate oxidative stress, decreasing markers thereof, improve cellular function, and reduce chronic inflammation. Recent clinical trials have found a bioactive in Weo water is able to significantly improve lipid status, reduce body fat percentage, arm fat index, decrease triglycerides & fasting insulin when compared to placebo water administration.  In vivo studies using Weo water have confirmed these findings,  showing positive effects of our water on specific features of metabolic syndrome, including protection from glucose dysregulation issues that can arise from a high fat, high sugar diet making Weo water a strategy for prevention of MS.

  • Korovljev D, Trivic T, Drid P, Ostojic SM. Molecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women. Ir J Med Sci. 2018 Feb;187(1):85-89. doi: 10.1007/s11845-017-1638-4. Epub 2017 May 30. PMID: 28560519.
  • LeBaron TW, Singh RB, Fatima G, Kartikey K, Sharma JP, Ostojic SM, Gvozdjakova A, Kura B, Noda M, Mojto V, Niaz MA, Slezak J. The Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome: A Randomized Controlled Trial. Diabetes Metab Syndr Obes. 2020 Mar 24;13:889-896. doi: 
  • Korovljev D, Trivic T, Drid P, Ostojic SM. Molecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women. Ir J Med Sci. 2018 Feb;187(1):85-89. doi: 10.1007/s11845-017-1638-4. Epub 2017 May 30. PMID: 28560519.
  • O’Neill S, O’Driscoll L. Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies. Obes Rev. 2015 Jan;16(1):1-12. doi: 10.1111/obr.12229. Epub 2014 Nov 18. PMID: 25407540.
  • https://www.nhlbi.nih.gov/health/metabolic-syndrome#:~:text=Metabolic%20syndrome%20is%20common%20in,3%20adults%20have%20metabolic%20syndrome
  • Ohsawa, I., Ishikawa, M., Takahashi, K. et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med 13, 688–694 (2007). 
  • Todorovic, N.; Fernández-Landa, J.; Santibañez, A.; Kura, B.; Stajer, V.; Korovljev, D.; Ostojic, S.M. The Effects of Hydrogen-Rich Water on Blood Lipid Profiles in Clinical Populations: A Systematic Review and Meta-Analysis. Pharmaceuticals 2023, 16, 142.
  • Yang M, Dong Y, He Q, Zhu P, Zhuang Q, Shen J, Zhang X, Zhao M. Hydrogen: A Novel Option in Human Disease Treatment. Oxid Med Cell Longev. 2020 Sep 5;2020:8384742. doi: 10.1155/2020/8384742. PMID: 32963703; PMCID: PMC7495244.
  • Courturier K et al. Université Grenoble Alpes. Metabolic Syndrome and Weo Water. Weo Internal. Oct 2022. 

8.

Weo Technology Promotes Restructuring of Water Molecules

Similar to other sources of energy, such as electromagnetic energy from the sun, Weo technology uses electrical energy to create new species like H2, O2, and ROS by splitting the water molecules.Hydrogen bond network that exist between water molecules will be modified by the presence of newly created specie since they have different hydrogen bond ability either between themselves or between them and water molecules.

As a result a new hydrogen bond network will be created for and water molecules possess different hydrogen bonds, which results in restructured water and or the creation of potential energy.  Evidence for this includes internal research as well as research completed where the water produced from our patented BDD electrolysis resulted in water containing molecules with higher energy (-0.0074 eV) hydrogen bonds than both tap and hydrogen water.  The strength of the hydrogen bond decides water’s properties and activity.

For example, we know that hydrogen bonding plays a key role in the intermolecular energy transfer. Therefore, it follows that Weo water may have unique properties enabling benefits to cellular health. 

Conclusion

Weo Technology uses a patented diamond electrolysis technology to produce a unique water consisting of blended properties and constituents.  Weo’s innovative, sustainable technology using allows for the creation of enhanced water properties and sustained bioavailability. This is an important point of differentiation from competitors because unlike other metal electrodes, Weo’s BDD electrodes do not leach, thereby eliminating the risk of metal contamination during/after the electrolysis. Furthermore, they allow for the creation of a mix of species with enabling activities such as sustained selective antioxidant bioavailability. Not having a membrane allows for the creation of both H2, O2 and species created from their split and recombinations.

In addition, to the production of both oxygen and hydrogen species there is evidence to indicate that the water undergoes a structural and physical change that has been associated with the promotion of health benefits. Weo water positively impacts the intra- and intermolecular energy transfer of hydration shell biomolecular interaction such as the free energy landscape that governs the folding, structure, and stability of protein. Further, the molecular hydrogen formed with rearranged structures has multiple abilities including accelerated mobility due to elevated energy levels and a small size enabling penetration into both red blood cells and tissues which may result in the delivery of energy at the cellular level. 

These unique attributes of Weo technology and its novel water support the mechanisms for the positive effects, going beyond hydration, seen in the areas of aging, skin health, immunity and metabolic health.

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